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NCLEX-RN cheat sheet · Renal and urinary

AKI, CKD and dialysis

Three kinds of AKI, potassium, CKD stages and diet, fistula and peritoneal care

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Acute kidney injury is a sudden loss of kidney function, over hours to days, and is often reversible. Chronic kidney disease persists over months. When the kidneys fail, dialysis does part of their work, but it isn't a cure.

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At a glance

Three kinds of acute kidney injury

TypeWhat goes wrongExamples
PrerenalToo little blood reaches the kidneyBleeding, dehydration, shock, heart failure
IntrarenalThe kidney itself is damagedProlonged low flow, contrast dye, aminoglycosides, muscle breakdown
PostrenalUrine can't get outEnlarged prostate, a stone, a tumor

Treat the cause: The cause decides the treatment. An ultrasound is the preferred test for a blockage.

Chronic kidney disease stages

StageGFR (mL/min/1.73 m²)Meaning
190 or higherKidney damage, normal filtration
260 to 89Mild
330 to 59Moderate
415 to 29Severe
5Under 15Kidney failure: dialysis or transplant

Chronic: Damage or reduced filtration that persists over months, often silent until advanced. Diabetes and high blood pressure cause most cases.

AKI: signs and labs

  • Less urine is a common warning, but injury can be nonoliguric, found by a rising creatinine.
  • Low output: under 0.5 mL/kg/h, sustained. Watch the trend; report it promptly per protocol.
  • Overload: swelling, high blood pressure, crackles. Wastes: nausea, itching, confusion; asterixis, seizures.
  • Labs: creatinine and BUN rise, the filtration rate falls, potassium is high, sodium often low.

CKD: signs and labs

  • Overload: swelling, hypertension, breathlessness. Wastes: poor appetite, nausea, a metallic taste, itching, confusion.
  • Less erythropoietin: anemia and fatigue; bleeding comes more easily.
  • Phosphorus often rises and calcium falls, though it varies: follow the labs. Bones can weaken.
  • Labs: high creatinine and BUN, often high potassium and phosphorus, low calcium, anemia.

AKI care

  • High potassium is the most dangerous change: deadly rhythms. Watch for peaked T waves; report palpitations or a slow, irregular pulse. It may be lowered with insulin and glucose, or a binder.
  • Treat the cause. IV fluids go in cautiously, watching for overload; diuretics may help remove fluid.
  • Protein isn't cut to delay dialysis; sodium, potassium, phosphorus and fluid are limited as needed, fluid often matched to urine output.
  • Dialysis for dangerous potassium, confusion, severe overload or pericarditis; usually short term.
  • Intake and output: assistive staff can measure them, but you analyze the trends and report. Weigh daily, same scale, same time: 1 kg in a day is about 1 liter of fluid.
  • Check every drug dose against kidney function. Before contrast, ask about prior reactions and metformin, and check kidney function.

Plan working: Urine output recovering above 0.5 mL/kg/h, creatinine and potassium moving toward normal, a stable weight, less swelling.

CKD treatment and the kidney diet

What to know
Blood pressureControlling it slows the damage. An ACE inhibitor or ARB when indicated, especially with albuminuria: monitor creatinine and potassium, and never combine the two
PotassiumWhen high, limit bananas, oranges, potatoes, tomatoes, dried fruit. Avoid salt substitutes that contain potassium: check the label. Sodium polystyrene sulfonate may be ordered
SodiumGenerally under 2 g a day, with exceptions: avoid processed and canned foods
PhosphorusLimit dairy, nuts, seeds, colas; phosphate binders as prescribed. Calcium and vitamin D only as directed
Protein, fluidModerate, high-quality protein, with enough calories. In later stages, fluid is limited based on urine output
DrugsAnemia: erythropoietin-stimulating drugs and iron. Ask the provider before any over-the-counter drug, herb or supplement. Metformin isn't used when GFR is below 30 mL/min/1.73 m²

Individualized: A renal dietitian helps, because the diet is complex and set by labs and stage.

Three ways to replace the kidneys

HemodialysisPeritoneal dialysisContinuous (CRRT)
FilterA machine outside the bodyThe lining of the bellyA machine, slowly, around the clock
AccessFistula, graft or catheterA belly catheterA large-vein catheter: central line care
ScheduleAbout 4 hours, 3 times a weekDaily or nightly24 hours a day, for days or weeks
Best forMost clients, in a centerIndependent clients at homeUnstable clients in intensive care: removes fluid gently
WatchLow blood pressure, cramps, held medicinesPeritonitisPotassium, blood pressure, fluid balance

Hemodialysis

  • Know which medicines to hold before a session: some are dialyzed out, others add to low blood pressure. Ask when in doubt; give held doses after, as ordered.
  • Weigh before and after. Dry weight is the weight with no extra fluid: the goal by the end of each session.
  • Fast fluid shifts can drop blood pressure (weak, dizzy, nauseated): per protocol, pause removal, lower the head, give saline.
  • Diet: limit sodium, phosphorus and fluids, including fluid in foods. Add protein, because hemodialysis removes it.

Peritoneal dialysis

  • Fill, dwell, drain: an exchange. By hand, about 4 a day, dwells of 4 to 6 hours; a cycler does 3 to 5 overnight. Don't skip exchanges.
  • Wash hands and wear a mask when connecting; check each bag. Warm it to body temperature.
  • Full or bloated is expected; pain isn't. Clean the exit site daily with antiseptic.
  • Normal drainage is straw colored. Cloudy fluid, pain, fever, nausea: peritonitis. Report it at once.

Fistula and graft

  • A fistula joins an artery to a vein: the best long-term access, but it takes months to heal. A graft can be used sooner, but clots and infects more often. A catheter is temporary.
  • Protect the fistula arm: no blood pressures, blood draws, IVs or anything tight. It's used only for dialysis and isn't flushed.
  • Feel a thrill (vibration) and hear a bruit (whoosh): blood is flowing. A missing thrill or bruit may mean a clot: report it at once.

Priority and safety calls

  • ★ AKI with a potassium of 6.2 mEq/L, a BUN of 42 mg/dL and a weight gain: the potassium is the priority. Monitor the heart; report it now.
  • ★ Output under 0.5 mL/kg/h, sustained, or a rising creatinine: report it promptly per protocol.
  • Traps: potassium salt substitutes, pushing fluids when urine is scant, anti-inflammatory drugs for kidney clients.
  • A blood pressure cuff or IV on the fistula arm is a trap: use the other arm.
  • A blood pressure drug due right before hemodialysis: check whether to hold it.
  • ★ Peritoneal dialysis with pain, fever and cloudy drainage: report it now. Skipping an exchange isn't the nurse's call.

How the NCLEX tests it

  • Acute injury is sudden and often reversible: prerenal, intrarenal or postrenal.
  • Watch urine output, daily weights and potassium, and treat the cause.
  • Chronic disease is slow, usually from diabetes or hypertension, and staged by the filtration rate.
  • Fistula: no pressures, draws or IVs in that arm; feel the thrill and hear the bruit.
  • Peritoneal: fill, dwell, drain; mask and clean hands; cloudy fluid means peritonitis.
  • Continuous therapy: slow and nonstop, for unstable clients.

Practice it next

This sheet comes from Acute kidney injury and chronic kidney disease and Dialysis and continuous renal replacement in our NCLEX-RN course. Try free practice questions, or see the lessons it was written from.

Free NCLEX practice questionsThe NCLEX-RN course

Quick self-quiz

  1. Low urine output is under ___ mL/kg/h, sustained.
    Show answer0.5
  2. CKD stage 5 is a GFR under ___ mL/min/1.73 m².
    Show answer15
  3. Metformin isn't used when GFR is below ___ mL/min/1.73 m².
    Show answer30
  4. The best long-term hemodialysis access is a ___.
    Show answerfistula
  5. The vibration you feel over a working fistula is a ___.
    Show answerthrill
  6. Normal peritoneal drainage is ___ colored.
    Show answerstraw

Sources

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Educational use only. This sheet is a study aid for the NCLEX-RN, not a substitute for clinical judgment, your facility’s policy or the provider’s orders. Where practice varies, follow facility policy and state law. NCLEX® and NCLEX-RN® are registered trademarks of NCSBN, which does not endorse these materials.